Lupus Nephritis (SLE)

What is Lupus Nephritis?

Lupus Nephritis occurs when immune complexes (antibodies) deposit in the kidneys, causing inflammation and affecting their ability to filter waste and fluids properly.

It is one of the most serious complications of Systemic Lupus Erythematosus and can lead to chronic kidney disease if untreated.

Causes of Lupus Nephritis

The primary cause is autoimmune activity in SLE:

Immune system attacks healthy kidney tissue

Formation of immune complexes that deposit in glomeruli

Inflammation and scarring of kidney filters